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Myc coordinates transcription and translation to enhance transformation and suppress invasiveness

c‐Myc is one of the major human proto‐oncogenes and is often associated with tumor aggression and poor clinical outcome. Paradoxically, Myc was also reported as a suppressor of cell motility, invasiveness, and metastasis. Among the direct targets of Myc are many components of the protein synthesis m...

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Detalles Bibliográficos
Autores principales: Elkon, Ran, Loayza‐Puch, Fabricio, Korkmaz, Gozde, Lopes, Rui, van Breugel, Pieter C, Bleijerveld, Onno B, Altelaar, AF Maarten, Wolf, Elmar, Lorenzin, Francesca, Eilers, Martin, Agami, Reuven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687422/
https://www.ncbi.nlm.nih.gov/pubmed/26538417
http://dx.doi.org/10.15252/embr.201540717