Cargando…
Myc coordinates transcription and translation to enhance transformation and suppress invasiveness
c‐Myc is one of the major human proto‐oncogenes and is often associated with tumor aggression and poor clinical outcome. Paradoxically, Myc was also reported as a suppressor of cell motility, invasiveness, and metastasis. Among the direct targets of Myc are many components of the protein synthesis m...
Autores principales: | Elkon, Ran, Loayza‐Puch, Fabricio, Korkmaz, Gozde, Lopes, Rui, van Breugel, Pieter C, Bleijerveld, Onno B, Altelaar, AF Maarten, Wolf, Elmar, Lorenzin, Francesca, Eilers, Martin, Agami, Reuven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687422/ https://www.ncbi.nlm.nih.gov/pubmed/26538417 http://dx.doi.org/10.15252/embr.201540717 |
Ejemplares similares
-
p53 induces transcriptional and translational programs to suppress cell proliferation and growth
por: Loayza-Puch, Fabricio, et al.
Publicado: (2013) -
Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation
por: Slobodin, Boris, et al.
Publicado: (2017) -
Ribosome profiling reveals features of normal and disease-associated mitochondrial translation
por: Rooijers, Koos, et al.
Publicado: (2013) -
A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis
por: Li, Li, et al.
Publicado: (2021) -
LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS
por: Li, Li, et al.
Publicado: (2018)