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Thiopurine methyltransferase and treatment outcome in the UK acute lymphoblastic leukaemia trial ALL2003

The influence of thiopurine methyltransferase (TPMT) genotype on treatment outcome was investigated in the United Kingdom childhood acute lymphoblastic leukaemia trial ALL2003, a trial in which treatment intensity was adjusted based on minimal residual disease (MRD). TPMT genotype was measured in 23...

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Detalles Bibliográficos
Autores principales: Lennard, Lynne, Cartwright, Cher S, Wade, Rachel, Vora, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687427/
https://www.ncbi.nlm.nih.gov/pubmed/25940902
http://dx.doi.org/10.1111/bjh.13469