Cargando…

Thiopurine methyltransferase and treatment outcome in the UK acute lymphoblastic leukaemia trial ALL2003

The influence of thiopurine methyltransferase (TPMT) genotype on treatment outcome was investigated in the United Kingdom childhood acute lymphoblastic leukaemia trial ALL2003, a trial in which treatment intensity was adjusted based on minimal residual disease (MRD). TPMT genotype was measured in 23...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lennard, Lynne, Cartwright, Cher S, Wade, Rachel, Vora, Ajay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2015
Materias:	Paediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687427/ https://www.ncbi.nlm.nih.gov/pubmed/25940902 http://dx.doi.org/10.1111/bjh.13469

Ejemplares similares

Thiopurine dose intensity and treatment outcome in childhood lymphoblastic leukaemia: the influence of thiopurine methyltransferase pharmacogenetics
por: Lennard, Lynne, et al.
Publicado: (2014)

Meta-analysis of randomized trials comparing thiopurines in childhood acute lymphoblastic leukaemia
por: Escherich, Gabriele M, et al.
Publicado: (2011)

Distinctive genotypes in infants with T‐cell acute lymphoblastic leukaemia
por: Mansur, Marcela B., et al.
Publicado: (2015)

A survey on thromboprophylaxis and coagulation assessment in children and young adults with acute lymphoblastic leukaemia (ALL) in the Nordic and Baltic countries: Different practices of assessment and management
por: Andersson, Nadine G., et al.
Publicado: (2022)

Quality of life in mothers and fathers of children treated for acute lymphoblastic leukaemia in Sweden, Finland and Denmark
por: Mogensen, Nina, et al.
Publicado: (2022)

Thiopurine methyltransferase polymorphisms in children with acute lymphoblastic leukemia
por: Linga, Vijay Gandhi, et al.
Publicado: (2014)

Blinatumomab as bridging therapy in paediatric B‐cell acute lymphoblastic leukaemia complicated by invasive fungal disease
por: Yeoh, Daniel K., et al.
Publicado: (2022)

Assessment of Thiopurine–based drugs according to Thiopurine S-methyltransferase genotype in patients with Acute Lymphoblastic Leukemia
por: Azimi, F, et al.
Publicado: (2014)

Osteonecrosis in paediatric acute lymphoblastic leukaemia: Incidence, risk factors, radiological patterns and evolution in a single‐centre cohort
por: Brivio, Erica, et al.
Publicado: (2022)

Thiopurine methyltransferase genotyping in Palestinian childhood acute lymphoblastic leukemia patients
por: Ayesh, Basim Mohammad, et al.
Publicado: (2013)

Genetic Polymorphism of Thiopurine S-methyltransferase in Children with Acute Lymphoblastic Leukemia in Jordan
por: Alsous, Mervat, et al.
Publicado: (2018)

Evaluation of the pharmacokinetics of prednisolone in paediatric patients with acute lymphoblastic leukaemia treated according to Dutch Childhood Oncology Group protocols and its relation to treatment response
por: Sassen, Sebastiaan D. T., et al.
Publicado: (2021)

Health-related quality of life and its determinants during and after treatment for paediatric acute lymphoblastic leukaemia: a national, prospective, longitudinal study in the Netherlands
por: Schwartz, Emily R, et al.
Publicado: (2023)

Activity and toxicity of intramuscular 1000 iu/m(2) polyethylene glycol‐E. coli L‐asparaginase in the UKALL 2003 and UKALL 2011 clinical trials
por: Sidhu, Jasmeet, et al.
Publicado: (2022)

Pharmacogenetics of thiopurine therapy: from thiopurine S-methyltransferase to S-adenosylmethionine
por: Mlinarič-Raščan, Irena, et al.
Publicado: (2009)

Development and validation of a prognostic scoring model to risk stratify childhood acute myeloid leukaemia
por: Li, Jun, et al.
Publicado: (2022)

Thiopurine methyltransferase genotype and thiopurine S-methyltransferase activity in Greek children with inflammatory bowel disease
por: Gazouli, Μaria, et al.
Publicado: (2012)

Thiopurine Methyltransferase Activity and Thiopurine Metabolites in Inflammatory Bowel Disease
por: El-Matary, Wael
Publicado: (2020)

Clinical implication of thiopurine methyltransferase polymorphism in children with acute lymphoblastic leukemia: A preliminary Egyptian study
por: El-Rashedy, Farida H., et al.
Publicado: (2015)

Benefits of risk‐adapted and mould‐specific antifungal prophylaxis in childhood leukaemia
por: Meryk, Andreas, et al.
Publicado: (2020)

Thiopurine S-methyltransferase polymorphisms in acute lymphoblastic leukemia, inflammatory bowel disease and autoimmune disorders: influence on treatment response
por: Abaji, Rachid, et al.
Publicado: (2017)

PACSIN2 polymorphism is associated with thiopurine-induced hematological toxicity in children with acute lymphoblastic leukaemia undergoing maintenance therapy
por: Smid, Alenka, et al.
Publicado: (2016)

Osteonecrosis in patients with acute lymphoblastic leukaemia: a national questionnaire study
por: Amin, Nadia Laila, et al.
Publicado: (2017)

Pneumonia diagnosis in childhood and incidence of leukaemia, lymphoma and brain cancer: a Danish nationwide cohort study
por: Søgaard, Kirstine Kobberøe, et al.
Publicado: (2017)

COVID-19 symptom surveillance in immunocompromised children and young people in the UK: a prospective observational cohort study
por: Shaunak, Meera, et al.
Publicado: (2021)

Pharmacogenetic studies of thiopurine methyltransferase genotype‐phenotype concordance and effect of methotrexate on thiopurine metabolism
por: Zimdahl Kahlin, Anna, et al.
Publicado: (2020)

PKCζ and PKMζ are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity
por: Hartsink-Segers, S A, et al.
Publicado: (2015)

Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial
por: Schwab, Claire, et al.
Publicado: (2022)

Defining low-risk high hyperdiploidy in patients with paediatric acute lymphoblastic leukaemia: a retrospective analysis of data from the UKALL97/99 and UKALL2003 clinical trials
por: Enshaei, Amir, et al.
Publicado: (2021)

Thiopurine S-Methyltransferase and Methylenetetrahydrofolate Reductase Polymorphisms in Leukemia
por: KÜPELİ, Serhan
Publicado: (2015)

Thiopurine S-Methyltransferase Polymorphisms in Korean Dermatologic Patients
por: Lee, Minseok, et al.
Publicado: (2017)

Tonsillectomy among children with low baseline acute throat infection consultation rates in UK general practices: a cohort study
por: Koshy, Elizabeth, et al.
Publicado: (2015)

NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells
por: Somazu, Shinpei, et al.
Publicado: (2021)

Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re‐sensitization by JNK inhibition
por: Nicholson, Lindsay, et al.
Publicado: (2015)

Thiopurine methyltransferase (TPMT) genotyping to predict myelosuppression risk
por: Nguyen, Christine M., et al.
Publicado: (2011)

Polymorphisms of the thiopurine S-methyltransferase gene among the Libyan population
por: Zeglam, Hamza Ben, et al.
Publicado: (2015)

Pharmacogenetic testing for thiopurine drugs in Brazilian acute lymphoblastic leukemia patients
por: Suarez-Kurtz, Guilherme, et al.
Publicado: (2023)

Not all that looks fractured is broken—multipartite humeral epicondyles in children
por: Schmid, Andrea, et al.
Publicado: (2022)

Assessment of healthcare delivery in the early management of bacterial meningitis in UK young infants: an observational study
por: Okike, Ifeanyichukwu O, et al.
Publicado: (2017)

Is 6-thioguanine more appropriate than 6-mercaptopurine for children with acute lymphoblastic leukaemia?
por: Lennard, L., et al.
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_1q69on7qhk43g11qrct1153svv