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Characteristics of α-Gal epitope, anti-Gal antibody, α1,3 galactosyltransferase and its clinical exploitation (Review)

The α-Gal epitope (Galα1,3Galα1,4GlcNAc-R) is ubiquitously presented in non-primate mammals, marsupials and New World Monkeys, but it is absent in humans, apes and Old World monkeys. However, the anti-Gal antibody (~1% of immunoglobulins) is naturally generated in human, and is found as the immunogl...

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Detalles Bibliográficos
Autores principales: HUAI, GUOLI, QI, PING, YANG, HONGJI, WANG, YI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687435/
https://www.ncbi.nlm.nih.gov/pubmed/26531137
http://dx.doi.org/10.3892/ijmm.2015.2397