Profound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus

Acquired uniparental disomy (aUPD) is a common finding in myeloid malignancies and typically acts to convert a somatically acquired heterozygous mutation to homozygosity. We sought to identify the target of chromosome 14 aUPD (aUPD14), a recurrent abnormality in myeloid neoplasms and population coho...

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Detalles Bibliográficos
Autores principales: Chase, A, Leung, W, Tapper, W, Jones, A V, Knoops, L, Rasi, C, Forsberg, L A, Guglielmelli, P, Zoi, K, Hall, V, Chiecchio, L, Eder-Azanza, L, Bryant, C, Lannfelt, L, Docherty, L, White, H E, Score, J, Mackay, D J G, Vannucchi, A M, Dumanski, J P, Cross, N C P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687469/
https://www.ncbi.nlm.nih.gov/pubmed/26114957
http://dx.doi.org/10.1038/leu.2015.130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687469/
https://www.ncbi.nlm.nih.gov/pubmed/26114957
http://dx.doi.org/10.1038/leu.2015.130

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