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Formulation of Anti-miR-21 and 4-Hydroxytamoxifen Co-loaded Biodegradable Polymer Nanoparticles and Their Antiproliferative Effect on Breast Cancer Cells

[Image: see text] Breast cancer is the second leading cause of cancer-related death in women. The majority of breast tumors are estrogen receptor-positive (ER+) and hormone-dependent. Neoadjuvant anti-estrogen therapy has been widely employed to reduce tumor mass prior to surgery. Tamoxifen is a bro...

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Detalles Bibliográficos
Autores principales: Devulapally, Rammohan, Sekar, Thillai V., Paulmurugan, Ramasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687493/
https://www.ncbi.nlm.nih.gov/pubmed/25880495
http://dx.doi.org/10.1021/mp500852s