Safety and tolerability considerations in the use of sildenafil for children with pulmonary arterial hypertension

Sildenafil is a phosphodiesterase type-5 inhibitor approved for treatment of pulmonary arterial hypertension (PAH) in adults. Data from pediatric trials demonstrate a similar acute safety profile to the adult population but have raised concerns regarding the safety of long-term use in children. Inte...

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Detalles Bibliográficos
Autores principales: Dodgen, Andrew L, Hill, Kevin D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687613/
https://www.ncbi.nlm.nih.gov/pubmed/26719728
http://dx.doi.org/10.2147/DHPS.S65571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687613/
https://www.ncbi.nlm.nih.gov/pubmed/26719728
http://dx.doi.org/10.2147/DHPS.S65571

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