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Safety and tolerability considerations in the use of sildenafil for children with pulmonary arterial hypertension
Sildenafil is a phosphodiesterase type-5 inhibitor approved for treatment of pulmonary arterial hypertension (PAH) in adults. Data from pediatric trials demonstrate a similar acute safety profile to the adult population but have raised concerns regarding the safety of long-term use in children. Inte...
Autores principales: | Dodgen, Andrew L, Hill, Kevin D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687613/ https://www.ncbi.nlm.nih.gov/pubmed/26719728 http://dx.doi.org/10.2147/DHPS.S65571 |
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