Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction

Viruses impose diverse and dynamic challenges on host defenses. Diversifying selection of codons and gene copy number variation are two hallmarks of genetic innovation in antiviral genes engaged in host-virus genetic conflicts. The myxovirus resistance (Mx) genes encode interferon-inducible GTPases...

Descripción completa

Detalles Bibliográficos
Autores principales: Mitchell, Patrick S., Young, Janet M., Emerman, Michael, Malik, Harmit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687636/
https://www.ncbi.nlm.nih.gov/pubmed/26658285
http://dx.doi.org/10.1371/journal.ppat.1005304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687636/
https://www.ncbi.nlm.nih.gov/pubmed/26658285
http://dx.doi.org/10.1371/journal.ppat.1005304

Ejemplares similares