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Reduction of blood pressure by store‐operated calcium channel blockers

The voltage‐operated Ca(2+) channels (VOCC), which allow Ca(2+) influx from the extracellular space, are inhibited by anti‐hypertensive agents such as verapamil and nifedipine. The Ca(2+) entering from outside into the cell triggers Ca(2+) release from the sarcoplasmic reticulum (SR) stores. To refi...

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Detalles Bibliográficos
Autores principales: Xu, Yan‐Jun, Elimban, Vijayan, Dhalla, Naranjan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687696/
https://www.ncbi.nlm.nih.gov/pubmed/26471725
http://dx.doi.org/10.1111/jcmm.12684