The IκB kinase inhibitor ACHP strongly attenuates TGFβ1‐induced myofibroblast formation and collagen synthesis

Excessive accumulation of a collagen‐rich extracellular matrix (ECM) by myofibroblasts is a characteristic feature of fibrosis, a pathological state leading to serious organ dysfunction. Transforming growth factor beta1 (TGFβ1) is a strong inducer of myofibroblast formation and subsequent collagen p...

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Detalles Bibliográficos
Autores principales: Mia, Masum M., Bank, Ruud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687706/
https://www.ncbi.nlm.nih.gov/pubmed/26337045
http://dx.doi.org/10.1111/jcmm.12661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687706/
https://www.ncbi.nlm.nih.gov/pubmed/26337045
http://dx.doi.org/10.1111/jcmm.12661

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