Bi-Allelic TCRα or β Recombination Enhances T Cell Development but Is Dispensable for Antigen Responses and Experimental Autoimmune Encephalomyelitis

Dual TCRα-expressing T cells outnumber dual TCRβ-expressing cells by ~10:1. As a result, efforts to understand how dual TCR T cells impact immunity have focused on dual TCRα expression; dual TCRβ expression remains understudied. We recently demonstrated, however, that dual TCRβ expression accelerate...

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Detalles Bibliográficos
Autores principales: Schuldt, Nathaniel J., Auger, Jennifer L., Hogquist, Kristin A., Binstadt, Bryce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687847/
https://www.ncbi.nlm.nih.gov/pubmed/26693713
http://dx.doi.org/10.1371/journal.pone.0145762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687847/
https://www.ncbi.nlm.nih.gov/pubmed/26693713
http://dx.doi.org/10.1371/journal.pone.0145762

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