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Risks and Benefits of Nalmefene in the Treatment of Adult Alcohol Dependence: A Systematic Literature Review and Meta-Analysis of Published and Unpublished Double-Blind Randomized Controlled Trials

BACKGROUND: Nalmefene is a recent option in alcohol dependence treatment. Its approval was controversial. We conducted a systematic review and meta-analysis of the aggregated data (registered as PROSPERO 2014:CRD42014014853) to compare the harm/benefit of nalmefene versus placebo or active comparato...

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Detalles Bibliográficos
Autores principales: Palpacuer, Clément, Laviolle, Bruno, Boussageon, Rémy, Reymann, Jean Michel, Bellissant, Eric, Naudet, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687857/
https://www.ncbi.nlm.nih.gov/pubmed/26694529
http://dx.doi.org/10.1371/journal.pmed.1001924