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Lipid raft–dependent plasma membrane repair interferes with the activation of B lymphocytes

Cells rapidly repair plasma membrane (PM) damage by a process requiring Ca(2+)-dependent lysosome exocytosis. Acid sphingomyelinase (ASM) released from lysosomes induces endocytosis of injured membrane through caveolae, membrane invaginations from lipid rafts. How B lymphocytes, lacking any known fo...

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Detalles Bibliográficos
Autores principales: Miller, Heather, Castro-Gomes, Thiago, Corrotte, Matthias, Tam, Christina, Maugel, Timothy K., Andrews, Norma W., Song, Wenxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687878/
https://www.ncbi.nlm.nih.gov/pubmed/26694840
http://dx.doi.org/10.1083/jcb.201505030