Cargando…

Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore

Kinetochores orchestrate mitotic chromosome segregation. Here, we use quantitative mass spectrometry of mitotic chromosomes isolated from a comprehensive set of chicken DT40 mutants to examine the dependencies of 93 confirmed and putative kinetochore proteins for stable association with chromosomes....

Descripción completa

Detalles Bibliográficos
Autores principales: Samejima, Itaru, Spanos, Christos, Alves, Flavia de Lima, Hori, Tetsuya, Perpelescu, Marinela, Zou, Juan, Rappsilber, Juri, Fukagawa, Tatsuo, Earnshaw, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687880/
https://www.ncbi.nlm.nih.gov/pubmed/26668330
http://dx.doi.org/10.1083/jcb.201508072