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Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore
Kinetochores orchestrate mitotic chromosome segregation. Here, we use quantitative mass spectrometry of mitotic chromosomes isolated from a comprehensive set of chicken DT40 mutants to examine the dependencies of 93 confirmed and putative kinetochore proteins for stable association with chromosomes....
Autores principales: | Samejima, Itaru, Spanos, Christos, Alves, Flavia de Lima, Hori, Tetsuya, Perpelescu, Marinela, Zou, Juan, Rappsilber, Juri, Fukagawa, Tatsuo, Earnshaw, William C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687880/ https://www.ncbi.nlm.nih.gov/pubmed/26668330 http://dx.doi.org/10.1083/jcb.201508072 |
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