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DNA Methylation in the Exon 1 Region and Complex Regulation of Twist1 Expression in Gastric Cancer Cells

Twist1 overexpression is frequently observed in various cancers including gastric cancer (GC). Although DNA methylation of the Twist1 gene has been reported in cancer cells, the mechanisms underlying transcriptional activation remain uncertain. In this study, we first examined epigenetic alterations...

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Detalles Bibliográficos
Autores principales: Sakamoto, Ayuna, Akiyama, Yoshimitsu, Shimada, Shu, Zhu, Wei-Guo, Yuasa, Yasuhito, Tanaka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687923/
https://www.ncbi.nlm.nih.gov/pubmed/26695186
http://dx.doi.org/10.1371/journal.pone.0145630