Beyond Mendelian randomization: how to interpret evidence of shared genetic predictors

OBJECTIVE: Mendelian randomization is a popular technique for assessing and estimating the causal effects of risk factors. If genetic variants which are instrumental variables for a risk factor are shown to be additionally associated with a disease outcome, then the risk factor is a cause of the dis...

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Detalles Bibliográficos
Autores principales: Burgess, Stephen, Butterworth, Adam S., Thompson, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687951/
https://www.ncbi.nlm.nih.gov/pubmed/26291580
http://dx.doi.org/10.1016/j.jclinepi.2015.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687951/
https://www.ncbi.nlm.nih.gov/pubmed/26291580
http://dx.doi.org/10.1016/j.jclinepi.2015.08.001

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