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Beyond Mendelian randomization: how to interpret evidence of shared genetic predictors
OBJECTIVE: Mendelian randomization is a popular technique for assessing and estimating the causal effects of risk factors. If genetic variants which are instrumental variables for a risk factor are shown to be additionally associated with a disease outcome, then the risk factor is a cause of the dis...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687951/ https://www.ncbi.nlm.nih.gov/pubmed/26291580 http://dx.doi.org/10.1016/j.jclinepi.2015.08.001 |