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Translational regulation of Inhibin βA by TGFβ via the RNA-binding protein hnRNP E1 enhances the invasiveness of epithelial-to-mesenchymal transitioned cells

The epithelial-to-mesenchymal transition (EMT) is a cellular process that functions during embryonic development and tissue regeneration, thought to be aberrantly activated in epithelial-derived cancer and play an important role in the process of metastasis. The TGFβ signaling pathway is a key induc...

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Detalles Bibliográficos
Autores principales: Howley, Breege V, Hussey, George S, Link, Laura A, Howe, Philip H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688046/
https://www.ncbi.nlm.nih.gov/pubmed/26096938
http://dx.doi.org/10.1038/onc.2015.238