MN1–Fli1 oncofusion transforms murine hematopoietic progenitor cells into acute megakaryoblastic leukemia cells

Long-term outcome of acute megakaryoblastic leukemia (AMKL) patients without Down's syndrome remains poor. Founding mutations and chimeric oncogenes characterize various AMKL subtypes. However, for around one third of all cases the underlying mechanisms of AMKL leukemogenesis are still largely...

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Detalles Bibliográficos
Autores principales: Wenge, D V, Felipe-Fumero, E, Angenendt, L, Schliemann, C, Schmidt, E, Schmidt, L H, Thiede, C, Ehninger, G, Berdel, W E, Arteaga, M-F, Mikesch, J-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688398/
https://www.ncbi.nlm.nih.gov/pubmed/26690545
http://dx.doi.org/10.1038/oncsis.2015.41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688398/
https://www.ncbi.nlm.nih.gov/pubmed/26690545
http://dx.doi.org/10.1038/oncsis.2015.41

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