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A novel approach for metabolic pathway optimization: Oligo-linker mediated assembly (OLMA) method

BACKGROUND: Imbalances in gene expression of a metabolic pathway can result in less-yield of the desired products. Several targets were intensively investigated to balance the gene expression, such as promoter, ribosome binding site (RBS), the order of genes, as well as the species of the enzymes. H...

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Detalles Bibliográficos
Autores principales: Zhang, Shasha, Zhao, Xuejin, Tao, Yong, Lou, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688952/
https://www.ncbi.nlm.nih.gov/pubmed/26702298
http://dx.doi.org/10.1186/s13036-015-0021-0