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A novel approach for metabolic pathway optimization: Oligo-linker mediated assembly (OLMA) method
BACKGROUND: Imbalances in gene expression of a metabolic pathway can result in less-yield of the desired products. Several targets were intensively investigated to balance the gene expression, such as promoter, ribosome binding site (RBS), the order of genes, as well as the species of the enzymes. H...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688952/ https://www.ncbi.nlm.nih.gov/pubmed/26702298 http://dx.doi.org/10.1186/s13036-015-0021-0 |