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Characterization of Toxoplasma gondii glyoxalase 1 and evaluation of inhibitory effects of curcumin on the enzyme and parasite cultures

BACKGROUND: The glyoxalase pathway, which includes two enzymes, glyoxalase 1 and 2 (Glo1 and Glo2), is a ubiquitous cellular system responsible for the removal of cytotoxic methylglyoxal produced during glycolysis. Protozoan parasites, including Toxoplasma gondii (T. gondii) tachyzoites, produce met...

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Detalles Bibliográficos
Autores principales: Goo, Youn-Kyoung, Yamagishi, Junya, Ueno, Akio, Terkawi, Mohamad Alaa, Aboge, Gabriel Oluga, Kwak, Dongmi, Hong, Yeonchul, Chung, Dong-Il, Igarashi, Makoto, Nishikawa, Yoshifumi, Xuan, Xuenan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688987/
https://www.ncbi.nlm.nih.gov/pubmed/26694921
http://dx.doi.org/10.1186/s13071-015-1268-5