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Characterization of Toxoplasma gondii glyoxalase 1 and evaluation of inhibitory effects of curcumin on the enzyme and parasite cultures
BACKGROUND: The glyoxalase pathway, which includes two enzymes, glyoxalase 1 and 2 (Glo1 and Glo2), is a ubiquitous cellular system responsible for the removal of cytotoxic methylglyoxal produced during glycolysis. Protozoan parasites, including Toxoplasma gondii (T. gondii) tachyzoites, produce met...
Autores principales: | Goo, Youn-Kyoung, Yamagishi, Junya, Ueno, Akio, Terkawi, Mohamad Alaa, Aboge, Gabriel Oluga, Kwak, Dongmi, Hong, Yeonchul, Chung, Dong-Il, Igarashi, Makoto, Nishikawa, Yoshifumi, Xuan, Xuenan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688987/ https://www.ncbi.nlm.nih.gov/pubmed/26694921 http://dx.doi.org/10.1186/s13071-015-1268-5 |
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