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Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? Study protocol for a randomised controlled trial

BACKGROUND: Osteoarthritis (OA) is a major clinical and public health problem, with no current medications approved as having disease modifying effects. HMG-CoA reductase inhibitors, or “statins”, a drug class widely used to prevent cardiovascular events, could potentially affect OA progression via...

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Detalles Bibliográficos
Autores principales: Wang, Yuanyuan, Tonkin, Andrew, Jones, Graeme, Hill, Catherine, Ding, Changhai, Wluka, Anita E., Forbes, Andrew, Cicuttini, Flavia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688994/
https://www.ncbi.nlm.nih.gov/pubmed/26700937
http://dx.doi.org/10.1186/s13063-015-1122-2