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iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function

BACKGROUND: SAFB1 is a RNA binding protein implicated in the regulation of multiple cellular processes such as the regulation of transcription, stress response, DNA repair and RNA processing. To gain further insight into SAFB1 function we used iCLIP and mapped its interaction with RNA on a genome wi...

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Detalles Bibliográficos
Autores principales: Rivers, Caroline, Idris, Jalilah, Scott, Helen, Rogers, Mark, Lee, Youn-Bok, Gaunt, Jessica, Phylactou, Leonidas, Curk, Tomaz, Campbell, Colin, Ule, Jernej, Norman, Michael, Uney, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689037/
https://www.ncbi.nlm.nih.gov/pubmed/26694817
http://dx.doi.org/10.1186/s12915-015-0220-7