IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis

Cancer-associated fibroblasts (CAFs) comprise one of the most important cell types in the tumor microenvironment. A proinflammatory NF-κB gene signature in CAFs has been suggested to promote tumorigenesis in models of pancreatic and mammary skin cancer. Using an autochthonous model of colitis-associ...

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Detalles Bibliográficos
Autores principales: Pallangyo, Charles K., Ziegler, Paul K., Greten, Florian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689166/
https://www.ncbi.nlm.nih.gov/pubmed/26621452
http://dx.doi.org/10.1084/jem.20150576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689166/
https://www.ncbi.nlm.nih.gov/pubmed/26621452
http://dx.doi.org/10.1084/jem.20150576

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