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IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis

Cancer-associated fibroblasts (CAFs) comprise one of the most important cell types in the tumor microenvironment. A proinflammatory NF-κB gene signature in CAFs has been suggested to promote tumorigenesis in models of pancreatic and mammary skin cancer. Using an autochthonous model of colitis-associ...

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Detalles Bibliográficos
Autores principales:	Pallangyo, Charles K., Ziegler, Paul K., Greten, Florian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689166/ https://www.ncbi.nlm.nih.gov/pubmed/26621452 http://dx.doi.org/10.1084/jem.20150576

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