Melanocyte antigen triggers autoimmunity in human psoriasis

Psoriasis vulgaris is a common T cell–mediated inflammatory skin disease with a suspected autoimmune pathogenesis. The human leukocyte antigen (HLA) class I allele, HLA-C*06:02, is the main psoriasis risk gene. Epidermal CD8(+) T cells are essential for psoriasis development. Functional implications...

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Detalles Bibliográficos
Autores principales: Arakawa, Akiko, Siewert, Katherina, Stöhr, Julia, Besgen, Petra, Kim, Song-Min, Rühl, Geraldine, Nickel, Jens, Vollmer, Sigrid, Thomas, Peter, Krebs, Stefan, Pinkert, Stefan, Spannagl, Michael, Held, Kathrin, Kammerbauer, Claudia, Besch, Robert, Dornmair, Klaus, Prinz, Jörg C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689169/
https://www.ncbi.nlm.nih.gov/pubmed/26621454
http://dx.doi.org/10.1084/jem.20151093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689169/
https://www.ncbi.nlm.nih.gov/pubmed/26621454
http://dx.doi.org/10.1084/jem.20151093

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