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Neuropilin 1 balances β8 integrin-activated TGFβ signaling to control sprouting angiogenesis in the brain

Angiogenesis in the developing central nervous system (CNS) is regulated by neuroepithelial cells, although the genes and pathways that couple these cells to blood vessels remain largely uncharacterized. Here, we have used biochemical, cell biological and molecular genetic approaches to demonstrate...

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Detalles Bibliográficos
Autores principales: Hirota, Shinya, Clements, Thomas P., Tang, Leung K., Morales, John E., Lee, Hye Shin, Oh, S. Paul, Rivera, Gonzalo M., Wagner, Daniel S., McCarty, Joseph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689212/
https://www.ncbi.nlm.nih.gov/pubmed/26586223
http://dx.doi.org/10.1242/dev.113746