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Neuropilin 1 balances β8 integrin-activated TGFβ signaling to control sprouting angiogenesis in the brain
Angiogenesis in the developing central nervous system (CNS) is regulated by neuroepithelial cells, although the genes and pathways that couple these cells to blood vessels remain largely uncharacterized. Here, we have used biochemical, cell biological and molecular genetic approaches to demonstrate...
Autores principales: | Hirota, Shinya, Clements, Thomas P., Tang, Leung K., Morales, John E., Lee, Hye Shin, Oh, S. Paul, Rivera, Gonzalo M., Wagner, Daniel S., McCarty, Joseph H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689212/ https://www.ncbi.nlm.nih.gov/pubmed/26586223 http://dx.doi.org/10.1242/dev.113746 |
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