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The auxin-inducible degradation (AID) system enables versatile conditional protein depletion in C. elegans

Experimental manipulation of protein abundance in living cells or organisms is an essential strategy for investigation of biological regulatory mechanisms. Whereas powerful techniques for protein expression have been developed in Caenorhabditis elegans, existing tools for conditional disruption of p...

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Detalles Bibliográficos
Autores principales: Zhang, Liangyu, Ward, Jordan D., Cheng, Ze, Dernburg, Abby F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689222/
https://www.ncbi.nlm.nih.gov/pubmed/26552885
http://dx.doi.org/10.1242/dev.129635