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Role of Oxidative Stress in Modulating Unfolded Protein Response Activity in Chronic Myeloid Leukemia Cell Line
BACKGROUND: Recently, it has been revealed that tyrosine kinase inhibitors (TKIs) act through inducing both oxidative and endoplasmic reticulum (ER) stress in chronic myeloid leukemia cells. However, ER stress signaling triggers both apoptotic and survival processes within cells. Nevertheless, mecha...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pasteur Institute of Iran
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689283/ https://www.ncbi.nlm.nih.gov/pubmed/26432458 http://dx.doi.org/10.7508/ibj.2016.01.009 |