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Role of Oxidative Stress in Modulating Unfolded Protein Response Activity in Chronic Myeloid Leukemia Cell Line

BACKGROUND: Recently, it has been revealed that tyrosine kinase inhibitors (TKIs) act through inducing both oxidative and endoplasmic reticulum (ER) stress in chronic myeloid leukemia cells. However, ER stress signaling triggers both apoptotic and survival processes within cells. Nevertheless, mecha...

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Detalles Bibliográficos
Autores principales: Bazi, Ali, Keramati, Mohammad Reza, Gholamin, Mehran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689283/
https://www.ncbi.nlm.nih.gov/pubmed/26432458
http://dx.doi.org/10.7508/ibj.2016.01.009