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Reactive Transformation and Increased BDNF Signaling by Hippocampal Astrocytes in Response to MK-801

MK-801, also known as dizocilpine, is a noncompetitive N-methyl-D-aspartic acid (NMDA) receptor antagonist that induces schizophrenia-like symptoms. While astrocytes have been implicated in the pathophysiology of psychiatric disorders, including schizophrenia, astrocytic responses to MK-801 and thei...

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Detalles Bibliográficos
Autores principales: Yu, Wenjuan, Zhu, Hao, Wang, Yueming, Li, Guanjun, Wang, Lihua, Li, Huafang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689377/
https://www.ncbi.nlm.nih.gov/pubmed/26700309
http://dx.doi.org/10.1371/journal.pone.0145651