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Network-Based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis
High-throughput mRNA sequencing (RNA-Seq) is widely used for transcript quantification of gene isoforms. Since RNA-Seq data alone is often not sufficient to accurately identify the read origins from the isoforms for quantification, we propose to explore protein domain-domain interactions as prior kn...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689380/ https://www.ncbi.nlm.nih.gov/pubmed/26699225 http://dx.doi.org/10.1371/journal.pcbi.1004465 |