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Distinctive Behaviors of Druggable Proteins in Cellular Networks
The interaction environment of a protein in a cellular network is important in defining the role that the protein plays in the system as a whole, and thus its potential suitability as a drug target. Despite the importance of the network environment, it is neglected during target selection for drug d...
Autores principales: | Mitsopoulos, Costas, Schierz, Amanda C., Workman, Paul, Al-Lazikani, Bissan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689399/ https://www.ncbi.nlm.nih.gov/pubmed/26699810 http://dx.doi.org/10.1371/journal.pcbi.1004597 |
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