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Memantine Attenuates Alzheimer’s Disease-Like Pathology and Cognitive Impairment
Deficiency of protein phosphatase-2A is a key event in Alzheimer’s disease. An endogenous inhibitor of protein phosphatase-2A, inhibitor-1, I(1) (PP2A), which inhibits the phosphatase activity by interacting with its catalytic subunit protein phosphatase-2Ac, is known to be upregulated in Alzheimer’...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689401/ https://www.ncbi.nlm.nih.gov/pubmed/26697860 http://dx.doi.org/10.1371/journal.pone.0145441 |