Non-Catalytic RISCs and Kinetics Determine Mammalian siRNA Sub-Cellular Localization

Small interfering RNAs (siRNAs) are fundamental to the regulation of cell function. Much is known about its gene interfering mechanism, but a kinetic description of it is still lacking. Here, we derived a set of reaction-diffusion equations for multiple RNA-induced silencing complex (RISC) pathways...

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Detalles Bibliográficos
Autores principales: Ji, Fengmin, Liu, Lianyun, Tien, Ya-Hsin, Peng, Yi-Hsien, Lee, Hoong-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689521/
https://www.ncbi.nlm.nih.gov/pubmed/26699128
http://dx.doi.org/10.1371/journal.pone.0143182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689521/
https://www.ncbi.nlm.nih.gov/pubmed/26699128
http://dx.doi.org/10.1371/journal.pone.0143182

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