Cargando…
Non-Catalytic RISCs and Kinetics Determine Mammalian siRNA Sub-Cellular Localization
Small interfering RNAs (siRNAs) are fundamental to the regulation of cell function. Much is known about its gene interfering mechanism, but a kinetic description of it is still lacking. Here, we derived a set of reaction-diffusion equations for multiple RNA-induced silencing complex (RISC) pathways...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689521/ https://www.ncbi.nlm.nih.gov/pubmed/26699128 http://dx.doi.org/10.1371/journal.pone.0143182 |