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A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions

BACKGROUND: A vaccine targeting Plasmodium vivax will be an essential component of any comprehensive malaria elimination program, but major gaps in our understanding of P. vivax biology, including the protein-protein interactions that mediate merozoite invasion of reticulocytes, hinder the search fo...

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Detalles Bibliográficos
Autores principales: Hostetler, Jessica B., Sharma, Sumana, Bartholdson, S. Josefin, Wright, Gavin J., Fairhurst, Rick M., Rayner, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689532/
https://www.ncbi.nlm.nih.gov/pubmed/26701602
http://dx.doi.org/10.1371/journal.pntd.0004264