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The Role of Symmetric Stem Cell Divisions in Tissue Homeostasis

Successful maintenance of cellular lineages critically depends on the fate decision dynamics of stem cells (SCs) upon division. There are three possible strategies with respect to SC fate decision symmetry: (a) asymmetric mode, when each and every SC division produces one SC and one non-SC progeny;...

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Detalles Bibliográficos
Autores principales: Yang, Jienian, Plikus, Maksim V., Komarova, Natalia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689538/
https://www.ncbi.nlm.nih.gov/pubmed/26700130
http://dx.doi.org/10.1371/journal.pcbi.1004629