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Mechanism of Iron-Dependent Repressor (IdeR) Activation and DNA Binding: A Molecular Dynamics and Protein Structure Network Study

Metalloproteins form a major class of enzymes in the living system that are involved in crucial biological functions such as catalysis, redox reactions and as ‘switches’ in signal transductions. Iron dependent repressor (IdeR) is a metal-sensing transcription factor that regulates free iron concentr...

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Detalles Bibliográficos
Autores principales: Ghosh, Soma, Chandra, Nagasuma, Vishveshwara, Saraswathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689551/
https://www.ncbi.nlm.nih.gov/pubmed/26699663
http://dx.doi.org/10.1371/journal.pcbi.1004500