Clobetasol and Halcinonide Act as Smoothened Agonists to Promote Myelin Gene Expression and RxRγ Receptor Activation

One of the causes of permanent disability in chronic multiple sclerosis patients is the inability of oligodendrocyte progenitor cells (OPCs) to terminate their maturation program at lesions. To identify key regulators of myelin gene expression acting at the last stages of OPC maturation we developed...

Descripción completa

Detalles Bibliográficos
Autores principales: Porcu, Giampiero, Serone, Eliseo, De Nardis, Velia, Di Giandomenico, Daniele, Lucisano, Giuseppe, Scardapane, Marco, Poma, Anna, Ragnini-Wilson, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689554/
https://www.ncbi.nlm.nih.gov/pubmed/26658258
http://dx.doi.org/10.1371/journal.pone.0144550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689554/
https://www.ncbi.nlm.nih.gov/pubmed/26658258
http://dx.doi.org/10.1371/journal.pone.0144550

Ejemplares similares