Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation

Post-transcriptional modifications of transfer RNAs (tRNAs) have long been recognized to play crucial roles in regulating the rate and fidelity of translation. However, the extent to which they determine global protein production remains poorly understood. Here we use quantitative proteomics to show...

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Detalles Bibliográficos
Autores principales: Deng, Wenjun, Babu, I. Ramesh, Su, Dan, Yin, Shanye, Begley, Thomas J., Dedon, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689569/
https://www.ncbi.nlm.nih.gov/pubmed/26670883
http://dx.doi.org/10.1371/journal.pgen.1005706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689569/
https://www.ncbi.nlm.nih.gov/pubmed/26670883
http://dx.doi.org/10.1371/journal.pgen.1005706

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