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Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation
Post-transcriptional modifications of transfer RNAs (tRNAs) have long been recognized to play crucial roles in regulating the rate and fidelity of translation. However, the extent to which they determine global protein production remains poorly understood. Here we use quantitative proteomics to show...
Autores principales: | Deng, Wenjun, Babu, I. Ramesh, Su, Dan, Yin, Shanye, Begley, Thomas J., Dedon, Peter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689569/ https://www.ncbi.nlm.nih.gov/pubmed/26670883 http://dx.doi.org/10.1371/journal.pgen.1005706 |
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