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Electrospun Zein/PCL Fibrous Matrices Release Tetracycline in a Controlled Manner, Killing Staphylococcus aureus Both in Biofilms and Ex Vivo on Pig Skin, and are Compatible with Human Skin Cells

PURPOSE: To investigate the destruction of clinically-relevant bacteria within biofilms via the sustained release of the antibiotic tetracycline from zein-based electrospun polymeric fibrous matrices and to demonstrate the compatibility of such wound dressing matrices with human skin cells. METHODS:...

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Detalles Bibliográficos
Autores principales: Alhusein, Nour, Blagbrough, Ian S., Beeton, Michael L., Bolhuis, Albert, De Bank, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689739/
https://www.ncbi.nlm.nih.gov/pubmed/26337770
http://dx.doi.org/10.1007/s11095-015-1782-3