Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells

The cholesterol metabolism is essential for cancer cell proliferation. We found the expression of genes involved in the cholesterol biosynthesis pathway up-regulated in the daunorubicin-resistant leukemia cell line CEM/R2, which is a daughter cell line to the leukemia cell line CCRF-CEM (CEM). Cellu...

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Detalles Bibliográficos
Autores principales: Stäubert, Claudia, Krakowsky, Rosanna, Bhuiyan, Hasanuzzaman, Witek, Barbara, Lindahl, Anna, Broom, Oliver, Nordström, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689760/
https://www.ncbi.nlm.nih.gov/pubmed/26698156
http://dx.doi.org/10.1007/s12032-015-0717-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689760/
https://www.ncbi.nlm.nih.gov/pubmed/26698156
http://dx.doi.org/10.1007/s12032-015-0717-5

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