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Effect of single doses of IV palonosetron, up to 2.25 mg, on the QTc interval duration: a double-blind, randomized, parallel group study in healthy volunteers

PURPOSE: The use of serotonin type 3 (5-HT(3)) receptor antagonists (RAs) in the prevention of nausea and vomiting caused by emetogenic chemotherapy is part of a comprehensive management strategy for patients undergoing chemotherapy. Electrocardiographic effects have been reported in patients after...

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Detalles Bibliográficos
Autores principales: Morganroth, Joel, Flaharty, Kristen K., Parisi, Simona, Moresino, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689761/
https://www.ncbi.nlm.nih.gov/pubmed/26111957
http://dx.doi.org/10.1007/s00520-015-2822-6