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B Cells in the Multiple Sclerosis Central Nervous System: Trafficking and Contribution to CNS-Compartmentalized Inflammation

Clinical trial results of peripheral B cell depletion indicate abnormal proinflammatory B cell properties, and particularly antibody-independent functions, contribute to relapsing MS disease activity. However, potential roles of B cells in progressive forms of disease continue to be debated. Prior w...

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Detalles Bibliográficos
Autores principales: Michel, Laure, Touil, Hanane, Pikor, Natalia B., Gommerman, Jennifer L., Prat, Alexandre, Bar-Or, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689808/
https://www.ncbi.nlm.nih.gov/pubmed/26732544
http://dx.doi.org/10.3389/fimmu.2015.00636